Charter Research contributes data toward FDA approval of donanemab.



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Every medical breakthrough we celebrate and benefit from is because of volunteers just like you. Everyday people who say “yes” to participating in clinical trials are changing the world for the better.

Explore our open studies — each one represents an opportunity to help build healthier futures.

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Obesity & Diabetes Trial

While weight management strategies exist, finding long-term solutions and understanding the root causes of obesity remain ongoing challenges. If you’re worried that you can’t manage your weight now or in the future, then joining an obesity study might be a great option for you. It might just help future generations, too.

Preliminary Qualifications

  • Clinical diagnosis of Type 2 diabetes
  • BMI > 30 or
  • BMI > 27 with hypertension, dyslipidemia, cardiovascular disease, or obstructive sleep apnea

Lung Research Studies

We’re validating a blood test to screen for lung cancer. We hope this innovative new test may one day indicate if you need further evaluation. Early detection matters. Detecting cancer early can improve treatment outcomes and survival. The 5-year survival rate for lung cancer is 8x higher if found before it spreads!  

Preliminary Qualifications

  • Current or former smoker
  • Age 50 years or older
  • Have scheduled or are willing to schedule a low-dose CT scan

Early Alzheimer’s Study

The purpose of this study is to find out if the study drug can slow or reverse early symptoms of Alzheimer’s disease. Some research has shown that people with Alzheimer’s disease have damage to the blood vessels in their brain. It is thought this new investigational drug may help the blood vessels in your brain work better.

Preliminary Qualifications

  • 50-90 years of age.
  • You have mild cognitive impairment or mild dementia consistent with Alzheimer's disease, but can complete most daily tasks independently.

Colorectal Cancer Blood Test

We're validating a blood-based diagnostic test to screen for colorectal cancer, in hopes this innovative new test may one day indicate if you need further evaluation.

Preliminary Qualifications

  • 45-84 years of age
  • Have, or will have, an upcoming colonoscopy
  • Considered by a physician or healthcare provider as being of 'average risk' for colorectcal cancer
  • Willing to consent to blood draw prior to bowel preparation and undergoing colonoscopy

Altimmune NASH Study

This study is for people with a diagnosis of non-alcoholic steatohepatitis (NASH), which is a condition that causes liver inflammation and damage due to a buildup of fat in the liver. The investigational drug, pemvidutide, is being developed as a possible treatment for NASH.

Preliminary Qualifications

  • 18-75 years of age.
  • Diagnosis of NASH.
  • BMI greater than or equal to 27.

Sensory Stimulation Alzheimer’s Study

The main purpose of this study is to see whether daily use of a device—called the "Sensory Stimulation System"—can help people with Alzheimer's-related memory problems. The device provides sensory stimulation via glasses worn on the face and headphones worn over the ears.

Preliminary Qualifications

  • 50-85 years of age.
  • Diagnosis of mild-to-moderate Alzheimer's disease.

Obesity Study

Obesity is a complex disease with many underlying causes and impacts on health. This study is to test a new drug with the potential to deliver substantial body weight reduction across the spectrum of obesity.

Preliminary Qualifications

  • You are at least 18 years of age.
  • You have a BMI greater than 35.
  • You have—or have experienced—one or more of the following: type 2 diabetes, heart attack, stroke, or peripheral arterial disease

“LMI” Tau Detection Study

The purpose of this study is to investigate the effectiveness and safety of a new injection—given in conjunction with a PET scan—to help detect tau protein in the brain. Early detection could help with the diagnostic process, as well as the treatment of, Alzheimer's disease.

Preliminary Qualifications

  • 50+ years of age.
  • A projected life expectancy of less than or equal to 1 year.
  • Study includes brain scan (PET scan).

“Avanir” Alzheimer’s Agitation Trial

This study evaluates a new medication to treat agitation in people with Alzheimer's disease. It is hoped this potential treatment could reduce caregiver burden and improve overall disease prognosis.

Preliminary Qualifications

  • 50-90 years of age.
  • Sometimes experience feelings of agitation.
  • Diagnosis of Alzheimer’s disease.

“Cerevel 002” Parkinson’s Disease Trial

We're testing an oral medication called Tavapadon as a possible treatment for Parkinson's disease over 35 weeks. Tavapadon aims to improve motor control symptoms.

Preliminary Qualifications

  • 40-80 years of age.
  • Have been diagnosed with Parkinson's disease within the last 3 years.

“Precision” NASH Trial

This quick study is to collect blood samples from people with various stages of fatty liver disease or NASH to support advancements in medical diagnoses of diseases such as fatty liver disease and NASH.

Preliminary Qualifications

  • 18 years of age or older.

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