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Alzheimer’s-Related Anxiety & Restlessness Study

New drug trial tests medication that could provide relief.

What is anxiety & restlessness in Alzheimer's?


PLEASE NOTE: This study is enrolling at the Orlando, FL and The Villages, FL research centers</strong

In addition to cognitive changes, Alzheimer’s can also lead to other symptoms: from finger tapping, nail biting, and restlessness to excessive motor activity, and verbal or physical outbursts. Also called agitation or (sometimes) sundowning, these symptoms are particularly challenging because there are currently no effective treatments.

This study medication holds promise in possibly relieving these types of symptoms, which appears in 40%–60% of Alzheimer patients and in 75% of moderate-to-severe dementia sufferers.

Who is eligible?

You may qualify for this study if:

  • You are able to travel to the research center in Orlando, FL or The Villages, FL.
  • The potential study volunteer is 55+ years of age.
  • There is a confirmed high likelihood of Alzheimer's disease, using either a blood-based biomarker or cerebrospinal fluid biomarker.
  • Any of the following are present (or similar traits not listed): pacing, rocking, restlessness, yelling, repetitive motor activity, scratching, slamming doors, finger tapping, or kicking objects.
  • Anxiety, restlessness, & agitation is not solely attributable to another psychiatric, medical, or environmental condition.

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